Antibacterial Activity of Gaharu (Aquilaria malaccensis Lamk) Against the Bacteria Streptococcus pyogenes
https://doi.org/10.52045/jca.v5i2.888
Keywords:
Antibacterial, Aquilaria malaccensis Lamk, Disc diffusion, Streptococcus pyogenesAbstract
Streptococcus pyogenes is a bacterium that causes throat and skin infections. Diseases caused by Streptococcus pyogenes bacteria can typically be treated with antibiotics. This study aims to determine the antibacterial activity of the ethanol extract of gaharu leaves (Aquilaria malaccensis Lamk) against the development of Streptococcus pyogenes bacteria using the disc diffusion method. The positive control used the antibiotic clindamycin, and the negative control used 1% DMSO. Observations were made by measuring the inhibition zone formed around the paper disc. The average diameter of the inhibition zone formed included a 10% concentration of 9.8 mm, a 15% concentration of 10.08 mm, a 20% concentration of 11.54 mm, and for the positive control, antibiotic clindamycin, it was 29.92 mm in the very strong category. In contrast, the negative control, 1% DMSO, did not form an inhibition zone. The One Way Anova data analysis test using the SPSS IBM version 26 program obtained results (p>0.05), meaning that there were significant antibacterial and differences in the diameter of the inhibition zone of the ethanol extract of gaharu leaves in each treatment.
Downloads
References
Asfi D, Yuliastuti R, Yusriyani. 2023. Uji Daya Hambat Ekstrak Etanol Daun Miana Merah (Coleus benth) Terhadap Staphylococcus aureus. Jurnal Kesehatan Yamasi Makassar, 7(1):10-16,
DOI https://doi.org/10.59060/jurkes.v7i1.238
Dong G, Liu H, Yu X, Zhang X, Lu H, Zhou T. 2018. Antimicrobial and anti-biofilm activity of tannic against Staphyllococcus aureus. Natural Product Research. 32(18): 2225–2228
DOI: https://doi.org/10.1080/14786419.2017.1366485
Febriyanti A. 2020. Aktivitas Antibakteri Ekstrak Etanol Daun Muda Daun Tua dan Daun Campuran Gaharu (Aquilaria malaccensis Lamk) Budidaya Terhadap Bakteri Streptococcus mutans. Skripsi. USU Press.
Hasanah MH, Apriyanti D, Patmayuni D. 2020. Perbandingan Antioksidan Ekstrak Etanol Daun Gaharu (Aqularia malaccensis L.) dan Ketiga Fraksi Berbagai Pelarut (Heksan, Etil Asetat, dan Air). Jurnal Penelitian Sains, 22(1):25-31, DOI: https://doi.org/10.56064/jps.v22i1.552
Hidayatullah SH, Mourisa C. 2023. Uji efektivitas akar karamunting (Rhodomyrtus tomentosa (Aiton) Hassk) terhadap pertumbuhan bakteri Staphylococcus aureus. Skripsi. UMSU Press.
Janshen YR, Sidharta BR, Swasti R. 2017. Aktivitas Antibakteri Ekstrak Daun Gaharu (Aquilaria malaccencis Lamk) Terhadap Pseudomonas aeruginosa dan Staphylococcus aureus. Fakultas Teknobiologi. Universitas Atma Jaya. Skripsi. Yogyakarta.
Kartikasari D, Ristia Rahman I, Ridha A. 2022. Uji Fitokimia Pada Daun Kesum (Polygonum minus Huds.) Dari Kalimantan Barat. Jurnal Insan Farmasi Indonesia. 5(1):35–42. DOI: https://doi.org/10.36387/jifi.v5i1.912
Khasanah D. 2020. Uji Fitokimia dan Toksisitas Ekstrak Umbi Hydnophytum sp. terhadap Artemia salina Leach. PENDIPA Journal of Science Education. 4(1): 47–53.
DOI: https://doi.org/10.33369/pendipa.4.1.47-53
Pranidya Tilarso D, Muadifah A, Handaru W, Pratiwi PI, Khusna ML. 2021. Aktivitas Antibakteri Kombinasi Ekstrak Daun Sirih Dan Belimbing Wuluh Dengan Metode Hidroekstraksi. Chempublish Journal. 6(2): 63–74. DOI: https://doi.org/10.22437/chp.v6i4.21736
Qomaliyah EN, Indriani N, Rohma A, Islamiyati R. 2023. Skrining Fitokimia, Kadar Total Flavonoid dan Antioksidan Daun Cocor Bebek. Current Biochemistry. 10(1):1–10. DOI: https://doi.org/10.29244/cb.10.1.1
Sari R, Muhani M, Fajriaty I. 2017. Uji Aktivitas Antibakteri Ekstrak Etanol Daun Gaharu (Aquilaria microcarpa Baill.) Terhadap Bakteri Staphylococcus aureus dan Proteus mirabilis. Pharmaceutical Science and Research. 4(3):143–54.
DOI: https://doi.org/10.7454/psr.v4i3.3756
Venesia, R. 2019. Uji Aktivitas Antibakteri Ekstrak Etanol Daun Gaharu (Aquilaria malaccensis Oken) Terhadap Staphylococcus epidermidis. KTI. Samarinda. Sekolah Tinggi Ilmu Kesehatan Samarinda.
Wardaniati, I. dan Gusmawarni, V. 2021. Uji Aktivitas Antibakteri Ekstrak Etanol Propolis Terhadap Streptococcus mutans. Jurnal Farmasi Higea, 13(2), 115-123.
DOI: 10.52689/higea.v13i2.372.
Za’amah Ulfah, Prastiwi R, Hayati H. 2021. Review Tanaman Gaharu (Aquilaria malaccensis Lam.) Ditinjau Dari Segi Farmakognosi, Fitokimia, dan Aktivitas Farmakologi. Jurnal Ilm Ilmu Kefarmasian. 8(2):105–14. DOI: https://doi.org/10.22236/farmasains.v8i2.5407
Zulita, Rani, Maudi Aulia, Nurhadini. 2018. Uji Aktivitas Antibakteri Ekstrak Daun Karamunting (Rhodomyrtus tomentosa) Terhadap Bakteri Staphylococcus aureus dan Shigella sp. Prosiding Seminar Nasional Penelitian dan Pengabdian Pada Masyarakat, 1(1):189. DOI: https://doi.org/10.33019/snppm.v2i0.618
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Nopriani Elianto, Sister Sianturi, Tria Saputra Saharuddin
This work is licensed under a Creative Commons Attribution 4.0 International License.
